Superglue - I use Loctite 454 for dopping, a gel superglue that is excellent for rough, uneven, or porous materials. It is amazing glue for dopping.
To flatten the "back" of a piece of rough opal I use a 360 grit diamond disc. I don't bother to go any finer because very often the profile of the stone can change as the opal is cut. In that case I end up changing the plane of the back. I do like to finish backs at 600, though.
Locktite 454 works great on flat surfaces ground with grits up to 600. I've tried it with stones and brass dops polished with 1200 and 1500. While for superglue you might expect that the flatter and smoother the better, but at those grits 454 fails for me. I can get through only a few wheels before the stone falls off. Though it does happen, it's unusual for that to happen for surfaces prepared with coarser grits. 454 seems to like surface defects!
The best deal is the 20 gram tube. The best deal on that is from this guy on eBay:
http://www.ebay.com/itm/LOCTITE-Instant-Adhesive-Cyanoacrylate-Super-Glue-ALL-/360485950460?pt=LH_De...If your more comfortable with Amazon, here is the best deal there:
http://www.amazon.com/Loctite-Prism-Surface-Insensitive-Adh/dp/B0001A3HRW/ref=sr_1_4?s=industrial&ie...Be sure to squeeze from the tail of the tube and to keep the nozzle clean. This stuff doesn't seem to dry up and clog like standard superglues, but you might at some point need to clear the tip with a needle. Keeping it refrigerated extends its life, but I don't bother. It just lasts and lasts.
Just a satisfied customer,
Gary