I second Claudia's post. I was trained in both Lectra & Optitex, but could afford neither as an independent. I decided on Cameo, and have been using it for about 8 years! It takes some getting used to...
I'll generally start a project by inputting the measurements into Cameo and use their pattern library to get close to the silhouette I want, print it out and do a muslin, drawing my changes/style lines on it, transfer those changes to the original paper pattern (legibly) and then input those changes back into Cameo and print the finished pattern.
The program is fully-functional, and if you're comfortable with pattern drafting, you can make Cameo sing! Anything it doesn't have a shortcut for I can usually figure out how to do it manually. The patterns look nice and clean. The marker/layout module is handy. You can also create specs and tech packs in it, though it's very labor-intensive and heavy on data-entry. I prefer to use Illustrator and Corel for the other stuff.
I purchased a used 36" plotter/printer from an architectural firm for $350. They were upgrading, but a basic plotter was perfect for my needs.
I use Cameo on a MacBook Pro running parallels. I don't really recommend that, as it's a huge memory-sucker and a couple of the minor functions don't work properly. I originally ran it on a PC laptop and it was much smoother, but that laptop died.