Keep print in mind when designing. All printers will print in one CMYK color profile or another. Its critical that you are designing in CYMK as well. Many bright, vibrant blues, and oranges simply cannot be printed in CMYK, and we must work around these issues. Always design for print, unless your a web designer.
Also, most production presses do not print 'white' as a color. The color white is determined by the paper you choose. For additional cost and set-up you can have white printed on a colored stock - but you’ll pay much steeper prices.